Evaluation of Biventricular Volume and Systolic Function in Children with Ventricular Septal Defect and Moderate to Severe Pulmonary Hypertension Using Real-Time Three-Dimensional Echocardiography

Background: Real-time three-dimensional echocardiography (RT-3DE) could obtain ventricular volume and ejection fraction rapidly non-invasively without relying on morphology. This study aims to use RT-3DE evaluate the changes in biventricular systolic function children with septal defect (VSD) moderate severe pulmonary hypertension (PH) before surgery. Methods: In this 18 VSD PH (VSD + Group) healthy of same age (Control were recruited. Biventricular evaluated by RT-3DE. The measurements included: left right indexed body surface area (BSA), stroke (SV) BSA, (EF). Results: results showed BSA SV significantly increased Group vs. Control Group), LVEDV/BSA (ml/m2 ): 48.67 ± 21.46 25.59 6.96, RVEDV/BSA 55.98 15.35 27.69 4.37, LVSV/BSA 24.08 9.30 15.14 4.29, RVSV/BSA 26.02 8.87 14.11 2.89, (P < 0.05). While for EF decreased LVEF: 50.93 7.50% 59.38 7.24%, RVEF: 45.84 7.71% 51.05 6.90% Conclusion: PH, observed RT-3DE, but remained within acceptable limits. recovered well after surgery serious perioperative complications, suggesting that may help facilitate surgical decision-making process moderate-tosevere PH.